利用实验室指标鉴别急、慢性胰腺炎及轻、重症胰腺炎

Identification of acute or chronic pancreatitis and mild or severe pancreatitis by using laboratory indicators

目的探讨急、慢性胰腺炎及轻、重症胰腺炎的鉴别指标。方法收集237例胰腺炎患者,记录其AMYL、TG、Ca^(2+)、CA199、WBC、N、Hb、RDW、PLT、PDW、CRP及PCT结果。将入选者分为急、慢性胰腺炎及轻、重症胰腺炎后进行组间比较,探讨2组的鉴别指标。结果急性、慢性胰腺炎组间的性别比例、血清AMYL、胰AMYL、Ca^(2+)、WBC、N、Hb及CRP结果差异均有统计学意义(P<0.05);进一步二分类Logistic回归,得出Ca^(2+)、N及Hb差异有统计学意义(P<0.05),急性胰腺炎血Ca^(2+)浓度较低,而N及Hb较高。轻症、重症胰腺炎组间的血AMYL、胰AMYL、TG、Ca^(2+)、WBC、N、RDW及PDW结果差异均有统计学意义(P<0.05);进一步二分类Logistic回归,得出2组间Ca^(2+)、N及TG差异有统计学意义(P<0.05),重症胰腺炎血Ca^(2+)浓度较低,而N及TG较高。结论 Ca^(2+)、N及Hb可鉴别急慢性胰腺炎,血Ca^(2+)浓度、N及TG可鉴别轻重症胰腺炎。

Objective To investigate the identification indicators of acute or chronic pancreatitis and mild or severe pancreatitis. Methods 237 cases of pancreatitis patients were collected,and the results of TG,Ca^2＋,AMYL,CA199,WBC,N,Hb,RDW,PLT,PDW,PCT and CRP were recorded. The selected patients were divided into acute and chronic pancreatitis,mild and severe pancreatitis,and comparisons of the indicators between acute and chronic pancreatitis,mild and severe pancreatitis were done to find the identification indicators. Results There was statistical significance on the difference of sex ratio,serum AMYL,pancreatic AMYL,Ca^2＋,WBC,N,Hb,and CRP between acute and chronic pancreatitis（ P〈0. 05）. Further Logistic regression found that the differences of Ca^2＋,N,Hb between the two groups were of statistical significance（ P〈0. 05）.Ca^2＋of acute pancreatitis was lower,N and Hb were higher. There were statistical significance on the differences of serum AMYL,pancreatic AMYL,TG,Ca^2＋,WBC,N,RDW and PDW between mild and severe pancreatitis（ P〈0. 05）. Further Logistic regression found that the differences among Ca^2＋,N,TG were of statistical significance（ P〈0. 05）. Ca^2＋of severe pancreatitis was lower,N and TG were higher. Conclusion N,Hb and Ca^2＋can be used to identify acute and chronic pancreatitis,Ca^2＋,N and TG can be used to identify the severity of pancreatitis.