医院真菌感染的调查分析

Investigation and analysis of nosocomial fungal infection

目的了解临床分离的酵母样真菌感染现状及分布特点,为减少真菌感染和控制医院感染提供实验依据。方法采用回顾性调查方法,对本院2013年1月-12月临床各科送检标本3 421份用沙保罗氏培养基和念珠菌显色培养基分离真菌,用ATB ID32C酵母菌鉴定板条鉴定真菌。结果临床标本共3 421份,培养阳性138份,阳性率为4.03%,符合医院感染共27例,其中局部感染25例,全身感染2例。全部患者均有基础性疾病,且均使用过多种广谱抗生素。结论医院酵母样真菌感染主要多发生于年老体弱、免疫功能低下、导管留置和长期使用广谱抗生素的患者,已成为医院感染的主要因素之一。

Objective To understand the status and distribution characteristics of yeast like fungal infection in clinical,so as to provide experimental evidence for reducing fungal infection and controlling nosocomial infection. Methods Retrospective investigation on 3 421 copies of clinical specimens during January-December in 2013 was carried out. Sabourand＇s medium and Candida color medium were used to isolate the fungi,using ATB ID32 C yeast identification strip for identification of fungi. Results A total of 3 421 clinical samples were detected,138 were positive,with positive rate of 4. 03%,there were 27 cases in line with the hospital infection,of which 25 cases were with local infection,2 cases were with systemic infection. All patients had basic diseases and a wide antibiotics use history. Conclusion Yeast like fungus infection mainly occurs on the old and weak patients with low immune function,indwelling catheter and long-term use of broad-spectrum antibiotics. This has become one of the main factors of hospital infection.