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肾移植术后细菌感染患者致病菌种分布及耐药性分析 被引量:9

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摘要 目的观察肾移植术后细菌感染患者致病菌种分布及耐药性。方法收集肾移植术后感染患者尿液、痰等标本进行细菌培养,对检出的206株致病菌进行菌种鉴定和药敏试验。结果 206株致病菌中革兰阴性菌173株(83.98%)、革兰阳性菌33株(16.02%)。大肠埃希菌(77株)、肺炎克雷伯菌(36株)、阴沟肠杆菌(13株)、粪肠球菌(10株)是主要致病菌。大肠埃希菌对氨苄西林、哌拉西林的耐药率高,分别为89.61%和93.91%;对喹诺酮类抗菌药物环丙沙星、左氧氟沙星的耐药率也较高,分别为70.13%和68.83%;对青霉素+酶抑制剂类的耐药率较低;检出1株耐美罗培南的大肠埃希菌,未检出对亚胺培南耐药的大肠埃希菌。肺炎克雷伯菌对氨苄西林、哌拉西林的耐药率较高,分别为86.11%和52.78%,未发现对亚胺培南和美罗培南耐药的菌株。表皮葡萄球菌对青霉素、氨苄西林、阿莫西林/克拉维酸钾、头孢曲松的耐药率为100%,对庆大霉素、左氧氟沙星、莫西沙星的耐药率低。金黄葡萄球菌对青霉素及左氧氟沙星的耐药率均为100%,对青霉素+酶抑制剂类抗菌药物耐药率低。未检出对万古霉素和利奈唑胺耐药的表皮葡萄球菌及金黄葡萄球菌。检出1株对万古霉素及利奈唑胺均耐药的粪肠球菌。结论肾移植术后感染患者致病菌种主要以革兰阴性菌为主,大肠埃希菌为主要致病菌,耐药性较高。
出处 《山东医药》 CAS 北大核心 2016年第26期80-82,共3页 Shandong Medical Journal
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参考文献16

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