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缓慢连续超滤治疗成年人肾病综合征重度浮肿的效果观察 被引量:3

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摘要 目的 探讨缓慢连续超滤(SCUF)治疗成年人肾病综合征重度浮肿的疗效与安全性。方法 选取成年人肾病综合征重度浮肿患者60例,采用随机数字表法随机分为A组和B组。A组给予改善循环、排毒、扩容利尿及原发病治疗等一般性治疗,B组在A组基础上给予SCUF脱水,治疗10~14 d后,记录两组治疗前后血白蛋白、血肌酐、血尿素氮、尿PCR、24 h尿量及体重变化;B组治疗前后血压、心率、凝血功能(PT、APTT)的变化。结果两组治疗后血肌酐、血尿素氮差异无统计学意义(P〉0.05),且组间比较差异无统计学意义(P〉0.05),B组患者治疗后血白蛋白、尿PCR、24 h尿量及体重改善程度与A组差异有统计学意义(P〈0.05)。B组治疗后收缩压、舒张压、心率较治疗前下降,差异有统计学意义(P〈0.05),但处于正常范围内;凝血功能与治疗前差异无统计学意义(P〉0.05)。结论 SCUF能在维持血压、心率较稳定时有效地改善重度浮肿症状,疗效确切、安全。
出处 《广东医学》 CAS 北大核心 2016年第13期1977-1979,共3页 Guangdong Medical Journal
基金 江西省卫生和计划生育委员会科技计划项目(编号:20151050)
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