高分辨磁共振成像3D-VISTA技术在检测脑微出血中的应用价值

The Application Value of High-resolution Magnetic Resonance Imaging Technology of 3D-VISTA on Detecting Cerebral Microbleeds

目的探讨高分辨磁共振成像3D-VISTA在检测脑微出血中的应用价值。方法回顾性分析65例初步诊断为淀粉样脑血管病患者头颅磁共振检查资料,分析图像质量并选择图像质量在合格以上资料。以磁敏感加权成像(SWI)序列检出脑微出血为标准,分区并且分级评价3D-VISTA序列、SWI序列及梯度回波T_2*成像(GRE)序列对脑微出血检出的一致性。结果 65例患者资料中,部分患者资料图像不合格,GRE序列、SWI序列及3DVISTA序列达到合格以上的患者分别为46、42及38例。3D-VISTA序列对淀粉样脑血管病患者脑微出血的检出情况与SWI序列检出情况一致性较好,Kappa值为0.6113。结论高分辨磁共振成像3D-VISTA技术在淀粉样脑血管病患者脑微出血的诊断中有一定的准确性。该技术能够应用于淀粉样脑血管病患者的筛查,为临床无创性诊断淀粉样脑血管病提供了新的方法。

Aim To investigate the application value of high-resolution magnetic resonance imaging technology of three-dimensional volumetric isotropic turbo spin echo acquisition（ 3D-VISTA） on detecting cerebral microbleeds（ CMB）.Methods 65 patients with cerebral amyloid angiopathy were retrospectively analyzed and carefully observed. In addition,all images were analyzed,and sieved from the class of being qualified and above. The present study detects the CMB by comparing two techniques to the ＂golden standard ＂ susceptibility weighted imaging（ SWI）,in order to assess the coherence of those techniques. And all CMBs were assessed by partitions and graded. Results Some cases of patients could not be applied because the images were unqualified,and the number of GRE sequence,SWI sequence and3D-VISTA sequence were 46,42 and 38,which could be applied. The results of 3D-VISTA sequence and SWI sequence had high consistency on detecting CMB of cerebral amyloid angiopathy（ CAA） patients,and the Kappa value was 0.6113.Conclusions The high-resolution magnetic resonance imaging technology of 3D-VISTA had expressed high accuracy in the diagnosis of CMB of CAA patients. The proposed technique of 3D-VISTA can be applied to detect the CAA,and it provides a useful noninvasive method for the diagnosis of CAA.