摘要
目的比较不同的脂肪乳治疗方案对早产极低出生体重儿的影响。方法选取2014年12月至2015年12月我院新生儿科收治的150例早产极低出生体重儿为研究对象,随机分为三组各50例。A组单纯采用葡萄糖、氨基酸治疗,不加脂肪乳;B组在葡萄糖、氨基酸治疗基础上于出生72 h给予20%中长链脂肪乳注射液;C组在葡萄糖、氨基酸治疗基础上于出生24 h给予20%中长链脂肪乳。比较三组患儿的体质量增长情况、达到全胃肠营养喂养时间的生化指标、喂养期间并发症情况。结果 C组的平均每日体质量增加量、达到全胃肠营养喂养时间、住院时间均显著优于其他两组,且B组患儿的以上指标显著优于A组(均P<0.05)。三组患儿在达到全胃肠营养喂养时间的总胆红素、谷丙转氨酶、三酰甘油、尿素氮比较均无统计学差异(P>0.05)。三组患儿的并发症发生率比较无统计学差异(P>0.05)。结论早产极低出生体重儿出生后早期应用脂肪乳能够迅速促进患儿的体质量增长,缩短住院时间,且患儿生化指标稳定,不会增加相关并发症发生率,值得临床推广和应用。
Objective To compare the impact of different treatment regimens of fat emulsion on premature infants with very lowbirth weight. Methods A total of 150 premature infants with very lowbirth weight in our hospital from D ecember 2014 to December 2015 were randomly divided into 3 groups, with 50 cases in each group. Group A was treated with single glucose and amino acid, without fat emulsion;on the basis of glucose and amino acid, group B was treated with 20% fat emulsion at 72 h after birth, while group Cwas treated with 20%fat emulsion at 24 h after birth. The infants＇ body mass growth, biochemical indicators at full parenteral nutrition feeding time and the complications during feeding were compared among three groups. Results In the indicators of average daily body mass increase, time of full parenteral nutrition feeding and length of hospital stay, group Cwas superior to the other two groups, and group B was superior to group A;Comparison between groups, all P〈0.05. No significant difference was found among 3 groups in the total bilirubin, ALT, triglycerides, urea nitrogen at the time of full parenteral nutrition feeding（P〈0.05）. No significant difference was found among 3 groups in the incidences of complications（all P〉0.05）. Conclusions E arly use of fat emulsion for premature infants with very lowbirth weight can quickly improve body mass increase, shorten hospital stay, and keep stable biochemical indicators, without increase of incidence of complications.
出处
《临床医学工程》
2016年第7期929-930,共2页
Clinical Medicine & Engineering
