女性免疫避孕的研究进展

Advances of female contraceptive vaccine

免疫避孕疫苗的发展在计划生育及控制人口方面具有重要意义。本文对国内外女性免疫避孕疫苗的研究情况,包括抗Gn RH疫苗、抗人绒毛膜促性腺激素疫苗及抗卵透明带疫苗的研究现状以及近年来取得的研究进展,进行了综述,重点阐述了抗卵透明带疫苗的发展历程。

The development of immunocontraceptive vaccines is important to birth control. In this article, we reviewed current progress in the research on the domestic and foreign female immunocontraceptive vaccines, including anti-gonadotropin-releasing hormone （GnRH） vaccine, anti-human chorionic gonadotrophin （hCG） vaccine and anti-zona pellucida （ZP） vaccine, especially focusing on the anti-ZP vaccine development.