过敏性休克诊断方法研究进展

Research Progress in Diagnosis of Anaphylactic Shock

过敏性休克发病急骤,难以预见,成为近年来引起医疗纠纷的重要原因之一。客观、科学、严谨和准确的法医学鉴定至关重要。当前过敏性休克死亡的法医学诊断主要是在排除其他疾病的基础上结合死者的病史、临床表现、组织病理学观察和生化指标检测做出诊断。由于过敏性休克临床表现和病理学形态没有特异性,也缺乏特异性的生化指标,过敏性休克的法医学鉴定仍然是一大难题。本文通过探讨过敏性休克的发生机制,对目前过敏性休克诊断的研究进展进行综述,并对下一步的研究作出展望。

Anaphylactic shock has an abrupt onset and is hard to be foreseen,which has become one of the important causes of medical disputes in recent years.An objective,scientific,rigorous and accurate forensic identification is essential for anaphylactic shock.The current forensic diagnosis of anaphylactic shock is mainly based on the medical history,clinical features,histopathological observations and biochemical tests in conjunction with the exclusion of other diseases.Because of the lack of specific clinical manifestations,pathologic morphology and biochemical markers,forensic identification of anaphylactic shock still remains a major problem.In this paper, we reviewed the recent progress in the pathogenesis and diagnosis of anaphylactic shock and discussed the prospect for further research.