急性病毒感染性腹泻病原体研究进展

Advances in the research of pathogens of acute viral infectious diarrhea

急性感染性腹泻是常见的肠道传染病之一,可由病毒、细菌、原虫等微生物及其产物致病,持续时间<2周的腹泻是其主要临床表现。研究表明,绝大多数急性感染性腹泻由病毒引起,可波及婴幼儿、成人和老人,直接或间接造成巨大的社会经济损失。随着分子生物学和细胞培养技术的发展,特别是聚合酶链反应(polymerase chain reaction,PCR)技术的应用,新的病毒不断发现,已知病毒不断深入探索。不同病毒所致急性胃肠炎的流行病学特征和临床症状存在差异,同样地,即便同种病毒,不同基因型的流行趋势、毒力大小也会有所变化。本文就常见的、重要的致泄性病毒作一概述。

Acute infectious diarrhea, associated with virus, b mon and complicated intestinal infectious diseases, of which cli shown that most cases of acute infectious diarrhea were caused by acteria, protozoan and their products, is nical symptom lasts less than 2 weeks. various viruses, which can affect infants, ／ a set of corn- Studies have children, adults and the elderly, and directly or indirectly induce heavy social and economic loss. With the progress of molecular biology and cell culture technology, especially the application of polymerase chain reaction （PCR） technology, unknown viruses are found and known viruses are constantly explored. Differences exist in the etiology, epidemiology and clinical symptoms of various viruses, which is the same as different subtypes and genotypes of a kind of virus. This article focused on viral diarrhea as follows.