76例早期胆囊癌的诊断及手术治疗预后分析

Diagnosis of 76 Cases of Early Gallbladder Cancer and Surgical Treatment Prognosis

目的探讨早期胆囊癌的诊断方法及术后预后的影响因素。方法选择76例早期胆囊癌患者,通过整理相关临床资料,对所有患者的治疗方法以及对影响患者预后的相关因素予以分析。结果采取单纯胆囊切除术中Ⅰ期患者24例,Ⅱ期患者21例;采取胆囊癌标准根治术中Ⅰ期患者5例,Ⅱ期患者14例;采取胆囊癌扩大根治术中Ⅰ期患者2例,Ⅱ期患者10例。所有患者术后均未出现死亡情况。1年生存率为100.00%,3年生存率为75.00%,5年存活率为44.74%。手术方式、Nevin分期、肿瘤所在位置、分化程度、黄疸为影响早期胆囊癌手术治疗预后的独立因素。结论根据早期胆囊癌患者不同的病理分期以及实际的侵犯范围,采取相应的手术治疗方式,能够提高患者的预后,延长生存时间。及时发现、正确的手术方式是提高其预后、延长生存期的关键。

Objective To investigate the diagnosis of early gallbladder cancer and correlative factors influencing the prognosis after surgery. Methods Diagnosis method,surgical treatment and correlative factors influencing the prognosis of 76 cases with early gallbladder cancer were analyzed through correlative factors. Results The simple cholecystectomy were 24 cases in stage Ⅰ,21 cases in stage Ⅱ. The gallbladder standard radical prostatectomy were 5 cases in stage Ⅰ,14 cases in stage Ⅱ. The gallbladder enlarge radical prostatectomy were 2 cases in stage Ⅰ,10 cases in stage Ⅱ. There had no death in all cases. 1-year survival rate was 100. 0%,3-year survival rate was 75. 00%,5-year survival rate was 44. 74%. The operation method,Nevin stage,tumor location,degree of differentiation and jaundice were independent factors influencing prognosis of early gallbladder cancer. Conclusion According to different pathological staging and the actual scope of infringement of early gallbladder cancer,corresponding surgical treatment can improve prognosis and prolong survival time. Timely discovery and correct operation method are the key of improving the prognosis and prolonging the survival time.