全聋型突发性聋的疗效及预后相关因素分析

Analysis of related prognostic factors and therapeutic effect of sudden sensorineural hearing loss with total hearing loss

目的探讨全聋型突发性耳聋的治疗效果及预后相关因素。方法回顾性分析2013年1月至2014年08月我院收治的全聋型突发性聋33例。遵循2005年中华医学会制定的突发性耳聋诊治指南,评估疗效并进行预后相关因素分析。结果 33例患者痊愈率为0,有效率为27.3%(9/33),显效率为21.2%(7/33),无效率为51.5%(17/33)。将年龄、性别、发病至初次就诊时间、有无耳鸣、有无眩晕等指标作为参数,进行疗效相关性检验,均未见统计学意义(P>0.05);但与伴有全身疾病者相比,不伴有全身疾病者具有相对较好疗效的趋势(P=0.086)。结论全聋型突发性聋的总体疗效不佳,本组资料未见明确的预后相关因素,但伴有全身疾病可能是预后不良的潜在风险因素。

Objective To investigate the therapeutic effect and related prognostic factors of sudden sensorineural hearing loss with total hearing loss. Method A retrospective ana Iysis was performed in 33 cases of sudden deafness patients during treatment from Janurary 2013 to August 2014 was conducted. To evaluate the therapeutic effect and analysis related factors of prognosis,all cases were conformed with guidelines for diagnosis and treatment of sudden sensorineural hearing loss by Chinese Medical Association in2005. Results In 33 cases, the full recover rate was 0, the effective percentage and significant effective percentage were 27.3%（9/33）and 21.2%（7/33）,the non-remission rate was 51.5%（17/33）. The relationship between age, gender,time period between onset and therapy, tinnitus,dizziness was analyzed. There was no significant difference（P〉0.05）. But the difference between the cases accompanied by systemic disease and not accompanied by systemic disease was significant.（P=0.086）. Conclusions The therapeutic effect of sudden sensorineural hearing loss with total hearing loss was poor. In this group, no related prognostic factors was found,but accompanied by systemic disease may be the potential risk factors of poor prognosis.