摘要
背景:Y形网片材料采取轻质聚丙烯材料编织,具有合适的孔隙率,可促进阴道组织在网片上迅速生长、融合的同时,保持良好的生物强度,保证骶骨前悬挂的固定力度。目的:回顾性分析Y形网片修复重建女性盆底功能的临床效果。方法:纳入女性盆底功能障碍性疾病患者10例,年龄37-73岁,均采用Y形网片进行腹腔镜下骶骨阴道悬吊治疗。记录围手术期并发症发生率,并对患者进行定期随访,记录不同时间点的POP-Q分期,采用PFIQ-7生活量表进行主观满意度调查。结果与结论:修复后随访至少6个月,所有患者术后无盆腔感染、神经损伤及并发症发生,愈合良好,未发生网片侵蚀、感染等不良反应;患者修复后1,3,6个月的POP-Q分期值较修复前明显改善(P<0.05),修复后1,3,6个月的PFIQ-7生活量表评分较修复前明显改善(P<0.05)。结果表明,采用Y形网片修复重女性中骨盆底功能缺陷具有良好的生物相容性,可恢复盆底解剖结构。
BACKGROUND: The Y-shaped mesh graft material weaved using lightweight polypropylen has the appropriate porosity, which not only can make the vaginal tissues grow and fuse rapidly on the mesh, but also can maintain good biological strength to ensure the fixed strength for the presacral suspension. OBJECTIVE: To retrospectively analyze the clinical effect of Y-shaped mesh for the biological function reconstruction of the female pelvic floor. METHODS: Ten female cases of pelvic floor dysfunction were enrolled, aged 37-73 years, and all were given the treatment of sacral colposuspension under laparoscopy. Then perioperative complications were recorded; patients were followed up regularly to record the Pelvic Organ Prolapse Quantification (POP-Q) score at different time points; and the subjective satisfaction was investigated using the Pelvic Floor Impact Questionnaire (PFIQ-7). RESULTS AND CONCLUSION: After at least 6-month follow-up, no postoperative pelvic infection, nerve damage and complications appeared, the patients healed well, and no mesh erosion, infection and other adverse reactions occurred. The POP-Q and PFIQ-7 scores at 1, 3 and 6 months after repair were significantly improved than those before repair (P 〈 0.05). These results suggest that the Y-shaped biological mesh repairing female midpelvic floor dysfunction has good biocompatibility, and can restore the anatomy of the pelvic floor.
出处
《中国组织工程研究》
CAS
北大核心
2016年第30期4503-4508,共6页
Chinese Journal of Tissue Engineering Research