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基于多组学平台的帕金森遗传变异研究进展 被引量:4

Research progress of Parkinson's genetic variation based on multi-omics platform
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摘要 “组学”是一种整体的研究思路,能提供一种非偏倚方法,鉴定涉及疾病的生物化学路径.最终,旨在确定未来值得靶向研究的一系列标志物。它包括基因组学、转录组学、蛋白组学及代谢组学。本文就近年来多组学协同发展及其在帕金森病的遗传变异研究中的作用进行综述。 "Omics" is a integral thought, which can provide a non-bias method, identify the biochemical pathways of the diseases, and ultimately determine the target for future research. It includes genomics, transcriptomics, proteomics and metabonomics. We elaborate the cooperative development of omics in recent years and it' s role in the genetic variation in Parkinson's disease in this article.
出处 《中华神经医学杂志》 CAS CSCD 北大核心 2016年第7期748-751,共4页 Chinese Journal of Neuromedicine
基金 国家卫生和计划生育委员会科研基金(WKJ-FJ-38) 福建省自然科学基金(2015J01686) 陈可冀中西医结合发展基金(CKJ2014012) 福建中医药大学校管重点学科专项(X2014010-学科)
关键词 组学 帕金森 遗传变异 Omics Parkinson Genetic variation
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