寒痹丸的质量标准研究

Study onquality standard of Hanbi Pill

目的建立寒痹丸的质量控制标准。方法对方中当归和川芎进行薄层色谱鉴别,同时采用HPLC法对淫羊藿中淫羊藿苷进行含量测定。结果薄层色谱中斑点清晰,专属性强;淫羊藿苷在10.15~81.20g/m L范围内与峰面积呈良好的线性关系,平均回收率为99.92%（RSD=1.34%）。结论本实验所用方法简便,重现性良好,定量方法准确可靠,可用于寒痹丸的质量标准控制。

Objective To establish the quality standard of Hanbi Pill. Methods A TLC method was used for qualitative i？dentification of the Radix Angelicae Sinensi and the Ligusticum chuanxiong Hort, and the Icariin was determined by HPLC. Results The TLC spots were clear, with strong specificity. The linear relationship of Icariin content was good in the range of 10. 15-81. 20 mg/mL, and the average recovery was 99.92% （ RSD=1.34%） . Conclusion The method is simple, accurate and reliable, with good reproducibility, and it can be used for the quality control of Hanbi Pill.