特发性草酸钙结石患者24h尿成石危险因素的分析

目的测定153例草酸钙结石患者24h尿量、尿草酸、尿枸橼酸、尿钙含量、并分析其与泌尿系结石形成的相关性。方法2014年7月至2015年10月共收集153例草酸钙结石患者的24h尿液，并测定其24h尿量、尿草酸、尿枸橼酸、尿钙的含量，并分析其与草酸钙结石形成的相关性。结果153例草酸钙结石患者，低尿量93例（60．7％），高钙尿症27例（17．6％），高草酸尿症98例（64．0％），低枸橼酸尿症121例（79．0％），男性患者与女性患者24h尿液定量分析比较：男性尿草酸和尿钙水平明显高于女性，差异有统计学意义（P〈O．05），其它指标差异无统计学意义（P〉0．05）。结论草酸钙结石患者常伴有低尿量、高钙尿、高草酸尿、低枸橼酸尿、且男性尿草酸和尿钙水平明显高于女性。

Objective Determination of 153 patients with calcium oxalate stones 24h urine, urinary oxalate, urinary citrate, urinary calcium and analyze the relationship between the results and urolithiasis. Methods the 24h urine of 153 patients with calcium oxalate stones were collected between July 2014 and October 2015, determination 24h urine volume, urinary oxalate, urinary citrate, urinary calcium were performed and the relationship between urolithiasis was analyzed. Reusults Among 153 case of patients low volume in 93 case （60.7%） , hypercalciuria in 27 case （ 17.6% ） , hyperoxaluria in 98 case （ 64.0% ） , hypocitraturia in 121 case （ 79.0% ） , the rate of hypercalciuria and hyperoxaluria of males is higher than females by the Student＇s t test （ P〈0.05 ） , others had no significant difference by the Student＇s t test （ P〉0.05 ） . Conclusions The patients with calcium oxalate stones relative high rate of low volume, hypercalciuria, hyperoxaluria and hypocitraturia, the rate of hypercalciuria and hyperoxaluria of males is higher than females.