联合检测血胃蛋白酶原和糖类抗原724在胃癌诊断中的价值

目的探讨血清胃蛋白酶原（PG）、糖类抗原724（CA724）对胃癌诊断的价值。方法选择2012年1月至2015年5月经临床手术及病理确诊的胃癌患者107例作为胃癌组。选择同期健康体检者100例作为对照组。采用放射免疫分析法检测两纽受试者的血清PG、CA724，并进行两组对照分析。结果胃癌组血清PGI、PGI／PGⅡ水平显著低于对照组（P〈0．01）、CA724水平显著高于对照组（P〈0．01）。单一检测血清PG或CA724的阳性率低于联合检测的阳性率（P〈0．05）。结论联合检测血清PG和CA724对胃癌的诊断有较高的价值。

Objective To study the diagnostic value of serum pepsinogen （ PG ） and carbohydrate antigen 724 （ CA72-4 ） in gastric cancer. Methods 107 patients with gastric cancer, who were diagnosed by surgery and pathology during Jan.2012 to May 2015, were studied as gastric cancer group.100 people who came for a healthy check-up during the same time were chosen as control group. Radiation immunity analysis was used to study the expression of PG and CA72-4 in these two groups. Comparison analysis was used for the data. Results The expression of PGI and PG I/PG lI in gastric cancer group was obviously lower than the control group （ P〈0.01 ） , while the expression of CA72-4 was obviously higher than the control group （P〈O.O1） .The positive rate of single test for PG or CA72-4was much lowerthan joint test of PGandCA72-4.Conclusion Joint test ofPG and CA72-4 has a diagnostic significance for gastric cance.