甲状腺钙化超声分型对甲状腺结节良恶性病变鉴别诊断能力的分析

Capability Calcification Thyroid Ultrasound Classification in the Diagnosis of Benign and Malignant Thyroid Nodules

目的探讨甲状腺钙化的超声分型对甲状腺结节良恶性病变鉴别诊断能力的分析。方法选取168例甲状腺癌患者作为研究组,选取同期204例甲状腺良性结节患者(271个结节)作为对照组,将两组患者甲状腺结节内的钙化进行超声分型,以术后病理结果为金标准,分析甲状腺结节内不同类型钙化与甲状腺良恶性病变的相关性。结果两组对比,甲状腺癌钙化发生率78.57%高于良性结节的10.70%,其中甲状腺癌微钙化发生率73.21%高于良性结节的3.32%,差异具有统计学意义(P<0.05),微钙化在甲状腺癌的诊断中的敏感性为73.21%,特异性为93.18%。粗大钙化及弧形钙化在两组中无显著性差异。结论钙化是甲状腺恶性病变鉴别诊断的特异性指标,其中微钙化对甲状腺癌的诊断具有高敏感性及特异性。

Objective To study the differentiation ability of thyroid nodules in thyroid nodules by ultrasonography. Methods A total of 168 cases of thyroid cancer patients were selected as the study group,and in addition to select 204 cases of benign thyroid nodule patients（271 nodules） as the control group,two groups of patients with thyroid nodule calcification ultrasound typing,and the pathology results as the gold standard,in order to analyze the correlation of thyroid nodules in different types of calcification and thyroid benign and malignant lesions. Results The calcification in thyroid cancer occurrence rate was 78.57%,which was significantly higher than that of benign nodules（10.70%）. Among them,micro-calcification in thyroid cancer occurrence rate was 73.21%,which was significantly higher than that of benign nodules（3.32%） and the difference was statistically significant between two groups（P〈0.05）,micro-calcification in thyroid cancer diagnosis sensitivity was 73.21% and the specificity was 93.18%. There was no statistically significant difference between two groups in the comparison of the gross calcification and the arc calcification. Conclusion The specific index for differential diagnosis of thyroid malignant lesions is calcification,which has the highest sensitivity and specificity in the diagnosis of thyroid carcinoma.