摘要
目的通过分析强直性脊柱炎术后临床病理分期,探讨腰背部椎旁肌有限剥离术缓解活动性强直性脊柱炎的疗效与临床病理分期的关系。方法 2007-2014年收集符合强直性脊柱炎诊断标准、资料完整的活动期患者127例,均实施了腰背部椎旁肌有限剥离术,观察术前术后Bath强直性脊柱炎病情活动性指数（BASDAI）,Bath强直性脊柱炎功能指数（BASFI）,Bath强直性脊柱炎测量指数（BASMI）,Bath强直性脊柱炎健康综合指数（BASG）评分,根据病理结合临床行分期,同时观察腰背部椎旁肌有限剥离术治疗强直性脊柱炎疗效与临床病理分期的关系。结果腰背部椎旁肌有限剥离手术无任何并发症、后遗症,腰部疼痛均有不同程度的缓解,BASDAI、BASFI与BAS-G 3项指标术后2周开始明显下降,而BASMI术后与术前相比未见明显差异。临床病理分为三期,临床症状改善情况与临床病理分期呈负相关关系,早期缓解明显,具有显著统计学意义。结论在病情早期实施腰背部椎旁肌有限剥离术能明显缓解活动性强直性脊柱炎临床症状,可有效抑制病情的进一步进展。
Objective Through the analysis of postoperative pathology and clinical staging of ankylosing spondylitis,the operation curative effect of low back paraspinal muscle limited dissection to alleviate the symptoms in patients of ankylosing spondylitis and the relationship with clinical pathology staging were evaluated. Methods 127 patients who were diagnosed with active ankylosing spondylitis were performed the operation of low back paraspinal muscle limited dissection. And the oberservation indicts including the BASDAI, BASFI, BASMI, BAS-G score were abtained respectively before surgery and after surgery 2,6,102 weeks, analysis of postoperative pathology and clinical staging of ankylosing spondylitis. Results There were no complications after operation in all cases and the symptoms decreased. BASDAI,BASFI and BAS-G indicts were decreased significantly compared with the conditions of before operation since 2 weeks after operation, There was no significant change about BASMI score after surgery（ P〈0.05）. Clinical pathology is divided into three phases, clinical symptoms improved negatively related with clinical pathologic staging, especially in the early state of AS has good effect with significant statistical significance. Conclusion This study confirms the operation could alleviate clinical symptoms of ankylosing spondylitis and effectively inhibit the further progress of the disease especially in the early state of AS.
出处
《生物骨科材料与临床研究》
CAS
2016年第3期59-62,共4页
Orthopaedic Biomechanics Materials and Clinical Study
基金
中山市科技计划项目(20122A047)
