不同类型早发型重度子痫前期患者期待治疗时间及妊娠结局的比较

Different types of early onset severe preeclampsia compare treatment time and look forward to the outcome of pregnancy

目的:探讨不同类型早发型重度子痫前期期待治疗时间以及妊娠结局。方法:选取我院产科在2010年6月至2015年6月期间收治的98例早发型重度子痫前期患者,并按照类型分为两组,观察组的50例患者为单纯早发型重度子痫前期,对照组的48例患者为慢性高血压并发早发型重度子痫前期,然后对两组患者的期待治疗时间、并发症的发生情况以及妊娠结局进行观察和对比。结果:观察组患者的期待治疗时间明显比对照组短(P<0.05);观察组患者肺水肿以及低蛋白血症的发生率明显比对照组高(P<0.05),两组患者发生视网膜剥脱、胎盘早剥、HELLP综合征、子痫、肝功能损害等并发症的发生率没有明显差异,其差异没有统计学意义(P>0.05);观察组胎儿生长受限的发生率明显低于对照组(P<0.05);两组出现新生儿窒息、胎死宫内、新生儿死亡、围产儿死亡的发生率没有显著性差异(P>0.05)。结论:与单纯性早发型重度子痫前期患者相比,慢性高血压并发早发型重度子痫前期患者的期待治疗时间明显要长,通过适当的观察及治疗措施,可在一定程度上延长患者的孕周,并降低围产儿的死亡率。

Objective：To investigate the different types of early onset severe preeclampsia expectant treatment time, and pregnancy outcomes. Methods： obstetric hospital in June 2010-98 cases of early onset severe preeclampsia admitted to June 2015 period, and 50 patients were divided according to the type groups, the observation group was simply early-onset severe preeclampsia early, 48 patients in the control group for chronic hypertension early onset severe preeclampsia, and two groups of patients expected duration of treatment, the incidence of complications and pregnancy outcomes were observed and compared. Results： The patients expect treatment time was significantly shorter （P 〈 0. 05） than the control group; the incidence of the observation group were pulmonary edema and hypoproteinemia significantly higher than the control group （P 〈 0.05）, two groups of patients with retinal exfoliation no significant difference in the incidence of placental abruption, HELLP syndrome, eclampsia, liver damage and other complications, the difference was not statistically significant （P 〉 0. 05） ;observation group the incidence of fetal growth restriction was significantly lower than the control group （P 〈 0. 05） ; the two groups appear asphyxia, fetal death, neonatal deaths, perinatal mortality rate was not significantly different （P 〈 0. 05）. Conclusion：Compared with simple early onset severe preeclampsia, chronic hypertension early onset severe preeclampsia expect significantly longer duration of treatment, observation and treatment through appropriate measures may have to some extent prolong gestational age, and reduce perinatal mortality.