大肠癌术后患者检测CEA值的临床意义(附300例报告)

Significance of Postoperative Elevation of Serum Carcinoembryonic Antigen in Colo-rectal Cancer

从1986.3.～1989.3.在300例大肠癌病人中,用单克隆抗体酶免疫法作了血清癌胚抗原的测定。在300例病人中有101例病人CEA值高于5ng/ml(占总病例的33.1％),在101例阳性病例中,术后复发与远处转移者72例(占71.3％)。本文作者对大肠癌术后血清CEA值增高与诊断、预后、复发再手术及姑息性观察治疗的关系作了进一步分析。

From 1986, 3, to 1989, 3, serum carcinoembryonic antigen (CEA) was assessed in 300 cases of colo-rectal cancer after operation by monoclonal antibody in immunoperoxidase technique. Elevated serum CEA was not specifically associated with colo-rectal cancer, but in 50 to 80％ of cases having metastases, the serum CEA levels were elevated without exception. The rapid rise of the serum CEA after operation suggested the presence of metastasis or residual cancer. If CEA level is found to be elevated in the follow-up period, recurrence of cancer is likely. Using serum CEA tesa as a guide to the adoption of adjuvant therapy after operation or as a basis for a 'second-look' laparatomy deserves further investigation.