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暂时性新生儿糖尿病临诊应对 被引量:1

Approach to the patients with transient neonatal diabetes mellitus
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摘要 暂时性新生儿糖尿病是一种少见的特殊类型糖尿病,需与1型糖尿病相鉴别,基因检测可协助进一步诊断分型,精确制定治疗方案及预测复发。磺脲类药物能改善这类患儿的胰岛素分泌,从而控制血糖。本文详细介绍1例暂时性新生儿糖尿病的诊治经过,以便临床医生重视该疾病的诊治。 [Summary] Transient neonatal diabetes mellitus is a kind of rare special types of diabetes. It should be distinguished from type 1 diabetes. Genetic analysis can be used to define the subtype of neonatal diabetes mellitus, which helps us to select the most appropriate treatment and to predict the disease recurrence. Sulfonylureas is able to improve insulin secretion in most patients with transient neonatal diabetes mellitus and provide effective glycemic control. A case of transient neonatal diabetes mellitus is reported in order to call attention to the diagnosis and treatment of this disease.
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2016年第6期510-513,共4页 Chinese Journal of Endocrinology and Metabolism
关键词 暂时性新生儿糖尿病 基因 磺脲类药物 Transient neonatal diabetes mellitus Gene Sulfonylureas
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  • 1Iafusco D,Massa O,Pasquino B,Colombo C,Iughetti L,Bizzarri C,et al.Minimal incidence of neonatal/infancy onset diabetes in Italy is 1:90 000 live births.Acta Diabetologica 2012; 49:405-408.
  • 2Sperling MA.Neonatal diabetes mellitus:from understudy to center stage.Curr Opin Pediatr 2005; 17:512-518.
  • 3Docherty LE,Kabwama S,Lehmann A,Hawke E,Harrison L,Flanagan SE,et al.Clinical presentation of 6q24 transient neonatal diabetes mellitus (6q24 TNDM) and genotype-phenotype correlation in an international cohort of patients.Diabetologia 2013; 56:758-762.
  • 4Mackay DJ,Temple IK.Transient neonatal diabetes mellitus type 1. Am J Med Genet C Semin Med Genet 2010; 154C:335-342.

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