基于文献探讨冠心病痰瘀互结证动物模型的评价标准

Evaluation criteria of coronary artery disease animal models with pattern of turbid phlegm with blood stasis: a literature study

冠心病痰瘀互结证是冠心病中的主要证候类型,以冠心病痰瘀互结证为研究对象,运用系统的检索方法,设定严格的纳排标准,搜集数据库中关于冠心病痰瘀互结证动物模型的文献。通过对纳入文献的评价指标进行分析,探索评价冠心病痰瘀互结证动物模型成功与否的客观标准和特异性标准,为制定科学的冠心病痰瘀互结证动物模型评价标准提供思路。

Taking pattern of turbid phlegm with blood stasis as the subject,which is the main TCM pattern of coronary artery disease（CAD）according to epidemiological investigation,we used systematic retrieval methods to find all papers linked to CAD animal models with pattern of turbid phlegm with blood stasis （hereinafter：animal models）under strict inclusion and exclusion criteria.We attempted to find out the objective standards and specific standards to evaluate whether the animal models were established successfully,in order to provide a foundation for making scientific evaluation standard of the animal mod-els.