摘要
原钙黏蛋白10(protocadherin 10,PCDH10),是一种表达于细胞膜表面的钙黏蛋白,属于原钙黏蛋白家族中的一员。最先发现在中枢神经系统中起作用,随着研究的深入,其参与肌动蛋白组装、参与认知功能的调节及抑癌等不为人知的功能逐渐被发掘出来。笔者将PCDH10的研究最新进展进行综述。
Objective: Protocadherin 10 (PCDH 10) is a kind of calcium mucins expressed in the surface of the cell membrane, belonging to a member the protocadherin family. At first, it had been found to play a role in the central nervous system. However, with the deepening of the researches, it has been found to participate in actin assembly, regulation of cognitive function, tumor-inhibition, and the like. The article reviews the latest research progress of PCDH 10.
出处
《华夏医学》
CAS
2016年第3期192-195,共4页
Acta Medicinae Sinica
基金
国家自然科学基金资助项目(81360386)
广西青年科学基金资助项目(2013GXNSFBA019165)