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原钙黏蛋白10的研究进展 被引量:4

Research progress of PCDH 10
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摘要 原钙黏蛋白10(protocadherin 10,PCDH10),是一种表达于细胞膜表面的钙黏蛋白,属于原钙黏蛋白家族中的一员。最先发现在中枢神经系统中起作用,随着研究的深入,其参与肌动蛋白组装、参与认知功能的调节及抑癌等不为人知的功能逐渐被发掘出来。笔者将PCDH10的研究最新进展进行综述。 Objective: Protocadherin 10 (PCDH 10) is a kind of calcium mucins expressed in the surface of the cell membrane, belonging to a member the protocadherin family. At first, it had been found to play a role in the central nervous system. However, with the deepening of the researches, it has been found to participate in actin assembly, regulation of cognitive function, tumor-inhibition, and the like. The article reviews the latest research progress of PCDH 10.
作者 江艳 叶元
出处 《华夏医学》 CAS 2016年第3期192-195,共4页 Acta Medicinae Sinica
基金 国家自然科学基金资助项目(81360386) 广西青年科学基金资助项目(2013GXNSFBA019165)
关键词 原钙黏蛋白10 结构特点 生物学功能 发病机制 PCDH10 structural feature bioloical function pathongenesis
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参考文献22

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二级参考文献84

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