2型糖尿病合并幽门螺杆菌感染致胰岛素抵抗一例报道并文献复习

Insulin Resistance Induced by Type 2 Diabetes Combined With Helicobacter Pylori Infection:A Case Report and Literature Review

幽门螺杆菌感染是发展中国家较为常见的细菌感染之一,对2型糖尿病患者代谢的影响尚存在争议。本文报道了1例2型糖尿病合并幽门螺杆菌感染老年女性患者的临床诊治经过,该患者同时存在幽门螺杆菌感染和严重胰岛素抵抗,排除其他可能导致胰岛素抵抗的病因后,随着幽门螺杆菌感染的好转胰岛素抵抗也同样得到改善,胰岛素用量降低,提示2型糖尿病合并幽门螺杆菌感染可导致胰岛素抵抗发生。目前,我国关于2型糖尿病合并幽门螺杆菌感染致胰岛素抵抗的报道较少,希望本文可以为2型糖尿病患者的胰岛素抵抗提供新的诊疗思路。

Pylori infection is a common kind of bacterial infection in developing countries, and the contoroversy about its influence on the metabolism of type 2 diabetes patients still exists. The paPer reported the process of the diagnosis and treatment of an elderly female patient with type 2 diabetes combined with helicobacter pylori infection. The patient had both pylori infection and severe insulin resistance. After the exclusion of other causes for insulin resistance, insulin resistance was eliminated with the recovery of helicobacter pylori infection, and the dosage of insulin was decreased. It suggested that type 2 diabetes combined with helicobacter pylori infection may induce insulin resistance. Currently, there are rare reports of insulin resistance induced by type 2 diabetes combined with helicobacter pylori infection. We hope this paper will provide new diagnostic thoughts for type 2 diabetes patients with insulin resistance.