MRI门静脉造影在恶性肝病预后的评估作用

The Evaluating Effect of MRI Portography in the Prognosis of Malignant Liver Disease

目的探讨MRI门静脉造影在评估恶性肝病预后中的作用。方法随机选取2012年1月至2014年4月我院收治的原发性肝癌患者100例,全部患者均行MRI门静脉造影(三维动态增强磁共振血管成像)检查,按照检查结果显示出门静脉系统受累的患者为阳性组50例,门静脉系统未受累的患者为阴性组50例,全部患者均行手术治疗。对比分析两组患者的门静脉血液动力学参数的改变情况并随访两组患者术后的1年、3年、5年生存率情况。结果经过MRI门静脉造影显示有门静脉受累的阳性组的血液动力学参数血流速度、血流量低于阴性组,差异具有统计学意义(P<0.05);有门静脉受累的阳性组的3年生存率为76.3%、5年生存率为41.1%,两项指标均明显低于阴性组的89.9%和57.4%,差异具有统计学意义(P<0.05)。结论 MRI门静脉造影可以良好显示门静脉受累情况并反映门脉受累后的血流动力学改变,对评估恶性肝病的预后具有重要价值。

Objective To evaluate the Effect of MRI Portography in the prognosis of malignant liver disease.Methods One hundred cases of primary liver cancer admitted in our hospital were randomly selected as the study subject from January 2012 to April 2014 and all underwent MRI Portography （three-dimensional dynamic contrast enhanced MR angiography, 3D DCE MRA） examination. The inspection showed 50 patients were positive in venous system involvement, and 50 patients were negative. All patients had surgical treatment. A comparative analysis of the two groups of patients with portal vein hemodynamic changes and follow-up of patients after two years, three years, five-year survival situation was made.Results The survival rate of 3 and 5 years in the positive group was 76.3%, 41.1% respectively, which were significantly lower than that of negative group（89.9% and 57.4%）, the difference was statistically significant （P〈0.05）.Conclusion The dynamic changes in MRI portography can be a predictor to the prognosis of patients with malignant liver disease.