健脾利水止痒方加减治疗原发性胆汁性肝硬化患者32例观察

Observation on treating 32 cases of primary biliary cirrhosis with the Jianpi Lishui Zhiyang prescription

目的:观察健脾利水止痒方对原发性胆汁性肝硬化合并腹水、皮肤瘙痒患者腹围、尿量、体重、皮肤瘙痒积分的影响。方法:对32例原发性胆汁性肝硬化合并腹水、皮肤瘙痒患者在休息、合理饮食及西医对症治疗基础上加用健脾利水止痒方治疗,疗程为3周。治疗期间每天早晨观察患者腹围、24h尿量、体重、皮肤瘙痒情况,比较治疗前后各指标的变化。结果:治疗后患者腹围、体重、尿量及皮肤瘙痒积分较治疗前均有明显改善,差异性显著(P<0.05)。结论:健脾利水止痒方加减联合西医常规治疗对原发性胆汁性肝硬化合并腹水、皮肤瘙痒患者具有较好的近期疗效,值得深入研究。

Objective： To observe the effect of the Jianpi Lishui Zhiyang prescription on abdominal circumference, urine volume, body weight, skin pruritus score in patients with primary biliary cirrhosis plus ascites, skin itching. Methods： On the basis of rest, reasonable diet and western medicine treatment, 32 cases of primary biliary cirrhosis with ascites, skin itching were treated with the Jianpi Lishui Zhiyang prescription, 3 weeks as a course. Abdominal circumference, 24 hours urine volume, weight, skin pruritus were observed every morning. The changes of each index before and after treatment were compared. Results： Abdominal circumference, body weight, urine and skin pruritus score were obviously improved after treatment. The difference was significant（P〈0.05）. Conclusion： The Jianpi Lishui Zhiyang prescription plus conventional western medicine on primary biliary cirrhosis with ascites, skin itching show a good curative effect in the near future, and is worthy of further study.