小儿重症腺病毒肺炎混合感染特征及高危因素分析

Analysis of Mixed Infection and High Risk Factors of Severe Adenovirus Pneumonia in Children

目的:分析小儿重症腺病毒肺炎的混合感染特征和其高危致病因素。方法:选取2013年6月-2015年4月在本院接受治疗的小儿腺病毒肺炎患儿74例,其中的29例重症腺病毒肺炎混合感染患儿为观察组,分析观察组的混合感染特征并研究危险因素。结果:29例重症腺病毒肺炎混合感染的患儿中,单纯腺病毒感染患儿8例(27.59%);合并其它类型感染21例(72.41%);多元Logistic回归分析结果发现,先天性心脏病、营养性贫血、多次发生肺部感染、既往存在手术病史、先天性气道发育异常,均是导致小儿重症腺病毒肺炎混合感染的高危因素(P<0.05)。结论:先天性心脏病、营养性贫血、多次发生肺部感染、既往存在手术病史、先天性气道发育异常,均是导致小儿重症腺病毒肺炎混合感染的高危因素。

Objective To analyze the characteristics and risk factors of severe adenovirus pneumonia in children. Methods74 children with adenovirus pneumonia in our hospital from June 2013 to April in were selected, and 29 cases of severe adenovirus pneumonia were selected as the observation group, and 45 cases as the control group, the mixed infection characteristics and risk factors were analyzed. Results 29 cases of mixed infection of severe adenovirus pneumonia in children, simple adenovirus infection in children in 8 cases（27.59 %）; with other types of infection in 21 cases（72.41 %）; multivariate logistic regression analysis showed that, congenital heart disease, nutritional anemia, multiple pulmonary infection, history of surgical history, congenital airway abnormalities are lead to children with severe adenovirus pneumonia mixture infection risk factors（P 0.05）. ConclusionCongenital heart disease, nutritional anemia, multiple pulmonary infection, past surgical history, congenital airway abnormalities are the high risk factors for the mixed infection of severe adenovirus pneumonia in children.