血清降钙素原与泌尿道感染尿培养相关性研究

Research of correlation between serum procalcitonin and urinary tract infection urine culture

目的探讨血清降钙素原(PCT)水平与泌尿道感染患者尿培养结果的关系,同时比较一般细菌感染和多重耐药菌感染患者中PCT的水平,评价血清PCT在泌尿道感染中的意义。方法 120例泌尿道感染患者作为观察组,50例体检健康者作为对照组,依据尿培养检查结果将观察组分为尿培养阳性组和尿培养阴性组,比较各组的血清PCT水平。结果尿培养阳性组PCT水平明显高于尿培养阴性组和对照组,差异具有统计学意义(P<0.05或0.01)。结论 PCT可以作为尿培养结果的重要依据,预测尿培养的结果 ,降低尿培养的假阳性率,同时可减少不必要的尿培养,从而降低患者的负担。

ObjectiveTo investigate relationship between serum procalcitonin （PCT） and urinary tract infection urine culture, to compare PCT levels between general bacterial infection and multi-drug resistant infection, and to evaluate significance by serum PCT in urinary tract infection.MethodsThere were 120 urinary tract infection patients as observation group and 50 healthy people as control group. The observation group was divided by urine culture outcomes into positive urine culture group and negative urine culture group. Serum PCT levels of all groups were compared.ResultsThe positive urine culture group had higher PCT level than the negative urine culture group and the control group, and their differences had statistical significance （P〈0.05 or 0.01）.ConclusionAs an important reference for urine culture outcome, PCT can predict outcome, reduce false negative rate and unnecessary urine culture, in order to reduce burden in patients.