心源性脑栓塞急性期抗栓治疗

Antithrombotic therapy for acute stage of cardiogenic cerebral embolism

了解心源性脑栓塞(CCE)急性期抗栓治疗的进展。回顾性分析近几年有关CCE急性期抗栓治疗的临床研究显示,阿司匹林可应用于所有脑梗死急性期(包括CCE);CCE急性期使用肝素类抗凝剂弊大于利;对伴有心房颤动(AF)的脑梗死患者,推荐使用华法林抗凝,但何时为最佳给药点尚缺乏足够证据。CCE急性期抗栓治疗中阿司匹林疗效肯定,华法林抗凝治疗亦有效,但何时启用尚未达成共识。

Progress of antithrombotic therapy for acute stage of cardiogenic cerebral embolism （CCE） was comprehended. A retrospective analysis was made on clinical research of antithrombotic therapy for acute stage of CCE in recent years, and that showed aspirin is suitable for all acute stage of cerebral infarction （including CCE）. Heparin anticoagulants provided more disadvantage than advantage for acute stage of CCE. Warfarin anticoagulation was recommended for cerebral infarction complicated with atrial fibrillation （AF） patients, while there was no sufficient evidence of the preferred medication time. Aspirin and Warfarin show effectiveness in anticoagulation for acute stage of CCE, while medication time needs discussion.