放大色素内镜在大肠肿瘤病灶形态与性质评价中的应用

Application of magnifying chromoendoscopy in the evaluation of large intestine tumor morphology and quality

目的：探讨放大色素内镜在大肠肿瘤病灶形态与性质评价中的应用价值。方法对82例接受内镜下粘膜切除术的大肠肿瘤患者运用放大色素内镜，将凹陷肿瘤病灶分为1型凹陷和2型凹陷，同时按照内镜下粘膜切除术之后的病理检查结果，判断大肠肿瘤病灶的形态与性质。结果本组患者病灶发生表面凹陷40例，其中1型凹陷病灶25例，2型凹陷病灶15例。2型凹陷病灶轻度增生发生率显著低于1型凹陷病灶，腺癌发生率显著高于1型凹陷病灶（P＜0．01）；2型凹陷病灶与1型凹陷病灶粘膜切除术浸润深度比较差异有显著性（P＜0．01）。结论在大肠肿瘤病灶形态与性质的评价中，放大色素内镜可依据大肠肿瘤表面的凹陷程度来判断病灶的浸润深度和性质，为内镜下粘膜切除术提供了重要的诊断依据，值得临床推广应用。

Objective To explore the application value of magnifying chromoen‐doscopy in the evaluation of large intestine tumor （LIT ） morphology and quality . Methods Excavated tumor foci of 82 LIT patients undergoing endoscopic mucosal resection （EMR） were assigned to type 1 and 2 excavation according to magnifying chromoendoscopy ,LIT morphology and quali‐ty judged according to pathological examination Results after EM R .Results Of the patients 40 ones de‐veloped surface excavation focus ,25 ones were type 1 excavation ,and 15 type 2 .The incidence of mild hy‐perplasia was significantly lower and that of adenocarcinoma higher （P〈0 .01） in type 2 than in type 1 ex‐cavation focus ;there was significant difference in invasion depth of EMR between type 2 and 1 excavation focus （P〈0 .01） .Conclusion Focus invasion depths and qualities could be judged according to LIT super‐ficial excavation degrees using magnifying chromoendoscopy in order to provide diagnostic basis for LIT , as deserves clinical generation and application .