甲氨蝶呤加物理疗法治疗缓解期类风湿关节炎伴腕关节受累的临床观察

Clinical Observation on the Treatment of Remission-stage Rheumatoid Arthritis with Wrist Joint Involvement with Methotrexate plus Physical Therapy

目的:探讨物理疗法对缓解期类风湿关节炎的临床疗效。方法:将60例缓解期类风湿关节炎患者随机分为治疗组29例和对照组31例。对照组采用甲氨蝶呤每周10 mg口服治疗;治疗组在对照组的基础上,采用汤岗子矿泥埋敷法和手部浸蜡疗法。2组疗程均为3个月。治疗前后对2组分别进行DAS28评分及关节活动度评价。结果:治疗后,治疗组DAS28评分与对照组相似,2组比较,差异无统计学意义(P>0.05)。但在关节活动范围的改善上,治疗组明显优于对照组,2组比较,差异有统计学意义(P<0.05)。结论:物理疗法配合标准药物治疗,能够更有效地控制缓解期类风湿关节炎活动性,同时,物理治疗配合药物治疗能够更有效地改善患者腕关节功能。

Objective：To explore the clinical effect of physical therapy on the treatment of rheumatoid arthritis in remission stage.Methods：Sixty patients with rheumatoid arthritis were randomly divided into a treatment group（29 cases） and a control group（31 cases）.Patients in the control group were treated with 10 mg methotrexate per week;while those in the treatment group were treated with Tanggangzi-slime-buried method and hand-dipped-in-wax therapy on the basis of the treatment for the control group.Both groups were treated for 3 months.Before and after treatment,the two groups were evaluated with DAS28 score and joint mobility. Results：After treatment,the DAS28 score of the treatment group was similar to that of the control group,and there was no significant difference between them（P〉 0.05）.But for the improvement of joint activity,the treatment group was significantly better than the control group,and the difference was statistically significant （P〈 0.05）.Conclusion：Physical therapy combined with standard drug therapy can effectively control the activity of rheumatoid arthritis in remission stage,and improve the function of wrist joint.