摘要
大肠癌(CRC)属于临床最常见的消化道肿瘤之一。大肠癌动物模型在简化复杂的发病机制和参与疾病的进展过程中至关重要。为此,本文综述了大肠癌动物模型建立方法、影响造模成功的因素等。
Colorectal cancer( CRC) is one of the most common clinical gastrointestinal cancer. Researchers,clinicians in colorectal cancer research in this area has been in continuous efforts. In this exploration of the road,the presence of colorectal cancer in animal models is unshakable. This paper reviews the methods of animal models of colorectal cancer,factors affecting successful model,and it's meaning,etc. to expand the discussion,provide a basis for a sense of colorectal further experimental research and clinical
出处
《中国临床药理学杂志》
CAS
CSCD
北大核心
2016年第14期1337-1340,共4页
The Chinese Journal of Clinical Pharmacology
基金
国家自然科学基金资助项目(81473482)
上海中医药大学"研究生创新"基金资助项目(2015YCX15)
关键词
大肠癌
化学诱导
移植模型
colorectal cancer
chemically-induced
transplantation model