实施试管婴儿治疗患者焦虑抑郁状态研究及其干预

Interventions treatment for IVF patients in anxiety and depression

实施试管婴儿治疗是一个长期慢性的过程,常常伴随取卵不利、胚胎数量少、移植失败等问题,因此患者容易产生焦虑和抑郁情绪。焦虑抑郁状态往往与治疗结局相关,这可能是由于其影响下丘脑—垂体—肾上腺轴、交感神经系统、免疫系统,扰乱激素正常分泌而导致的。目前,对于焦虑抑郁状态的调整主要采取认知和应对训练、心身治疗(包括瑜伽冥想放松)以及针药结合的方式。其中,中医辨证论治、针灸耳穴治疗在缓解患者心理压力状态,调节内分泌血激素水平,提高卵细胞胚胎质量,改善子宫内膜容受性,改善手术结局等方面均获得肯定疗效。

In Vitro Fertilization and Embryo Transfer treatment is a chronic process,often accompanied by poor oocyte retrieval,little embryos,implantation failure and many other problems,so patients prone to be anxiety and depression. Anxiety and depression are often associated with IVF treatment outcome,because they could influence the hypothalamic-pituitary-adrenal axis,the sympathetic nervous system,the immune system,and normal hormone secretion.At present,cognition and response training,psychosomatic treatment（ including yoga meditation relaxation） as well as a combination of traditional Chinese medicine and acupuncture is mainly taken to adjustment psychological stress. Among them,the traditional Chinese medicine,acupuncture and auricular therapy obtain a positive effect in relieving the psychological pressure state,regulation of blood hormone levels,improving embryo quality,endometrial receptivity and surgical outcomes.