中性粒细胞和淋巴细胞比率对急性冠脉综合征患者临床并发症的预测价值

Evaluation value of neutrophil to lymphocyte ratio for complications in patients with acute coronary syndromes

目的观察中性粒细胞和淋巴细胞比率（NLR）对急性冠脉综合征（ACS）患者临床并发症的预测价值。方法 184例ACS患者按NLR中位数分为A、B组,比较2组患者基础资料及住院期间恶性心律失常、心力衰竭、猝死发生率之间的差异。结果 B组C反应蛋白（CRP）、肌钙蛋白I、低密度脂蛋白胆固醇均较A组显著升高,差异具有统计学意义（P〈0.01）。B组的恶性心律失常、心力衰竭及猝死发生率均高于A组,差异有统计学意义（P〈0.05）。NLR升高与恶性心律失常[OR（95%CI）为1.97（1.09~3.57）]、心力衰竭[（OR（95%CI）为2.57（1.25~5.26）]、猝死[OR（95%CI）为8.67（1.06~70.77）]的发生有关。结论 NLR对ACS患者临床并发症有预测价值。

Objective To investigate the value of neutrophil to lymphocyte ratio（ NLR） in predicting the complications in patients with acute coronary syndromes（ ACS）. Methods A total of 184 patients with ACS were divided into group A and group B according to median of NLR. The basic data and complications between the two groups were compared. Results The levels of C-reactive protein,troponin I and low density lipoprotein were higher in group B than those in group A（ P〈0. 01）. The incidence rate of arrhythmia,heart failure and death in group B was higher than that in group A（ P〈0. 05）. Logistic regression showed that NLR was a prediction indicator of arrhythmia,heart failure and death.Conclusions NLR is a reliable indicator that can predict the complications of ACS.