芍药汤配合美沙拉嗪治疗溃疡性结肠炎疗效观察

Shaoyao Tang plus Mesalazine for Treating Ulcerative Colitis：Effect Observation

为观察中西药配合治疗溃疡性结肠炎（UC）的临床疗效，将120例溃疡性结肠炎患者随机分为对照组和观察组，每组各60例。对照组给予口服美沙拉嗪治疗，观察组在此基础上配合中药芍药汤口服。2周为1个疗程，3个疗程后比较两组疗效。结果显示，观察组的有效率（96．7％，58／60）显著高于对照组（63．3％，38／60），P〈0．05）；对2组78例治愈患者随访1年，观察组复发率（22．2％，10／45）显著低于对照组（72％，18／25）（P〈0．05）。结果表明，芍药汤配合美沙拉嗪口服治疗溃疡性结肠炎较单纯美沙拉嗪口服治疗临床疗效更为显著，且复发率低。

This study was to observe the clinical effect of UC treated with integration of Chinese materia media with western ones,randomly divided 120 UC patients into control group and observation one,60 ca- ses for each ; the former orally administered masalazine, while based on masalazine the latter added Shaoyao Tang（a Chinese medicine decoction-formula）,all lasted 3 treatment courses（2 weeks×3）;then both group ＂s effects were compared.As results,the effective rate of the latter was significantly higher than that of the former（96.7%,58/60 vs 63.3%,38/60, P 〈0.05）;after the follow-up of a year for 78 patients from 2 groups,the recurrence rate of the latter was signficantly lower than that of the former（22.2%, 10/45 vs 72%, 18/25, P 〈0.05）.Results show that Shaoyao Tang plus masalazine has more effective outcome,and lower recurrence rate.