胸腔镜手术治疗早期非小细胞肺癌的临床疗效

Thoracoscopic Surgery for Early-Stage Non-Small Cell Lung Cancer

目的观察胸腔镜手术治疗早期非小细胞肺癌的临床疗效。方法将98例早期非小细胞肺癌患者按随机数字表法分为治疗组与对照组,每组49例,治疗组行胸腔镜手术治疗,对照组予以开胸手术治疗。比较2组术中出血量及术后疼痛时间、拔管时间、恢复出院时间、并发症发生率;术后随访2年,比较2组存活率。结果治疗组术中出血量较对照组显著减少(P<0.05),术后疼痛时间、拔管时间及术后恢复出院时间均较对照组显著缩短(P<0.05),且术后并发症发生率较对照组明显降低(P<0.05)。术后随访2年,治疗组存活率为81.63%(40/49),对照组为77.55%(38/49),2组比较差异无统计学意义(P>0.05)。结论胸腔镜手术治疗早期非小细胞肺癌具有术中出血量少,术后疼痛减轻、恢复快、并发症少等特点,且手术治疗效果与传统的开胸手术相当。

Objective To observe the clinical efficacy of thoracoscopic surgery in the treatment of early-stage non-small cell lung cancer（ESNSCLC）.Methods Ninety-eight patients with ESNSCLC were randomly assigned to receive either thoracoscopic surgery（treatment group,n=49）or open thoracotomy（control group,n=49）.Intraoperative blood loss,postoperative pain time,extubation time,hospital discharge time and postoperative complications were compared between the two groups.Patients were followed up for 2years and the survival rate was recorded.Results Compared with control group,the intraoperative blood loss,postoperative pain time,extubation time,hospital discharge time and incidence of postoperative complications significantly decreased in treatment group（P〈0.05）.However,no significant difference in the survival rate was found between treatment group（81.63%,40/49）and control group（77.55%,38/49）（P〉0.05）.Conclusion Thoracoscopic surgery can reduce intraoperative blood loss and postoperative pain and complications and promote recovery in patients with ESNSCLC.In addition,the efficacy of thoracoscopic surgery is equivalent to that of open thoracotomy.