曲安奈德口腔软膏治疗糜烂型口腔扁平苔藓临床疗效观察被引量：29

The effect of triamcinolone acetonide dental paste in the treatment of erosive oral lichen planus

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摘要纳入60例经病理检查确诊的双侧颊黏膜为糜烂型扁平苔藓患者,以患者的一侧病损为试验组,患处涂抹曲安奈德口腔软膏,另一侧为对照组(不予任何治疗)。分别于初诊、第1、2、3、4周记录患者疼痛程度和糜烂面积的变化。用药后1、2、3、4周试验组患者的疼痛程度和糜烂面积明显改善(P<0.05),且优于同时间点的对照组(P<0.001)。2组均未见有不良反应。结果表明应用曲安奈德口腔软膏能有效治疗糜烂型口腔扁平苔藓。 60 patients with pathologically diagnosed erosive lichen planus of bilateral buccal mucosa were included. The lesion on one side was treated by local application of triamcinolone acetonide dental paste（ test group）,the lesion on the other side without treatment was used in the control group. 7,14,21 and 28 d after treatment the pain level and the lesion situation scores in the test group decreased significantly（ P 0. 001）,and lower than those in the control group at the same time point（ P〈0. 05）. No adverse reaction was found in the 2 groups.Triamcinolone Acetonide Dental Paste is effective in the treatment of erosive oral lichen planus.

作者李勉香吴桐杨灵澜李晓旭王娟夏娟

机构地区中山大学附属口腔医院.广东省口腔医学重点实验室

出处《实用口腔医学杂志》 CAS CSCD 北大核心 2016年第4期581-583,共3页 Journal of Practical Stomatology

关键词扁平苔藓(OLP) 糜烂曲安奈德 Oral lichen planus（OLP） Erosive Triamcinolone acetonide

分类号 R781.5 [医药卫生—口腔医学]

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