加味桃红四君子汤治疗青春期多囊卵巢综合征临床研究

Clinical Study of Modified Taohong Sijunzi Decoction in Treatment of Polycystic Ovary Syndrome in Adolescence

目的:观察加味桃红四君子汤治疗青春期多囊卵巢综合征的临床疗效。方法:将66例多囊卵巢综合征患者随机分为治疗组和对照组,每组33例。对照组服用达英-35治疗,治疗组在对照组治疗的基础上加服加味桃红四君子汤治疗,方药组成:桃仁15 g,红花15 g,党参25 g,炒白术15 g,茯苓15 g,鹿角霜15 g,当归15 g,香附15 g,杜仲15 g,炙甘草6 g。结果:治疗后治疗组有效率为93.94%,对照组有效率为75.76%,两组比较,差异有统计学意义(P<0.05)。治疗前后性激素水平、卵巢体积比较,差异有统计学意义(P<0.05)。结论:加味桃红四君子汤治疗青春期多囊卵巢综合征疗效显著,且可明显改善内分泌紊乱,重建月经和排卵周期。

Objective： To observe the clinical effect of Modified Taohong Sijunzi decoction in treatment of Polycystic Ovary Syndrome（ PCOS） occurs in adolescence. Methods： 66 cases of patients with PCOS were randomly divided into treatment group and control group,with 33 cases in each group. The control group was given Diane-35 in treatment,and the treatment groups received both Diane-35 and Modified Taohong Sijunzi decoction as prescription. Results： the clinical effect the treatment group（ 93. 94%）was superior to that of the control group（ 75. 76%）,the difference was statistical significance（ P 〈0. 05）. The sex hormone level and the ovarian volume of the both groups before and after treatment was statistically different（ P 〈0. 05）. Conclusion： Modefied Taohong Sijunzi Decoction can achieve better efficacy compared with that of the sole western medicine treatment in treating for Polycystic Ovary Syndrome（ PCOS） in adolescence and can obviously improve endocrine condition and regulate the menstrual and ovulation cycle. The combination of Chinese and western medicine in treating for Polycystic Ovary Syndrome（ PCOS） in adolescence is better than the sole western medical treatment with fewer side effects.