结构脂肪乳临床用药的合理性评价

Rationality Evaluation in Clinical Use of Structured Triglyceride

目的评价住院患者结构脂肪乳注射液(structured triglyceride,STG)的临床应用情况,以促进其合理应用。方法制定STG用药评价标准,采用回顾性分析方法,对STG的适应证、禁忌证、用法用量等进行合理性分析。结果共抽查2015年4月1日—5月31日使用STG住院患者368例,STG使用适应证合理率为60.60%,使用无禁忌证占86.96%,使用量合理率占84.24%,其他尚存在联合用药不合理(93.48%)、用药监测与给药滴速不规范等现象。结论本院临床使用STG不合理情况比较明显,医院应制定STG使用规范,加强用药干预,以改善STG不合理使用现状。

OBJECTIVE To investigate the clinical application and enhance rational use of structured triglyceride（STG）.METHODS This is a retrospective study using formulated STG usage evaluation standard to analysis the application rationality of STG in indications, contraindications, usage and dosage, etc. RESULTS Totally of 368 hospitalized patients administrated with STG were randomly collected from April 1 to May 31 st in 2015. The rates of rational use in indications, no contraindications, and dosage were 60.60%, 86.96% and 84.24%, respectively. In addition, other irrational phenomena were also existed, such as irrational use in combination medication（rate 93.48%）, inappropriate monitoring and dripping speed in STG transfusion. CONCLUSION The irrational phenomena of STG usage were clearly evident in our hospital. Thus, establishing standardized usage guideline for STG and strengthening the drug intervention is urgently needed to improve the current irrational usage situation of STG.