人参抗心律失常作用的文献再评价

Revaluation of Literatures on Antiarrhythimic Action of Ginseng

目的:对人参抗心律失常作用进行文献再评价。方法:通过查阅、归纳、整理2013年以前公开发表的有关人参皂苷抗心律失常作用的文献,根据药物药理作用的评价原则和抗心律失常作用的评定标准,对人参皂苷抗心律失常作用进行文献再评价,以明确其抗心律失常作用的确切性。结果:人参单体皂苷抗心律失常作用确切,依据充分;人参总皂苷、人参茎叶皂苷、人参果提取液、红参煎剂及人参制剂的抗心律失常作用实验依据不足,需进一步大样本研究。结论:人参单体皂苷具有显著的抗心律失常作用。

Objective：To revalue the literatures on the antiarrhythimic action of ginseng. Methods：By consulting, concluding and arranging literatures on the antiarrhythimic action of ginsenoside published before 2013, and based on the evaluation principle of its pharmacological action and the criteria of the antiarrhythimic action, the literatures on the antiarrhythimic action of ginsenoside were revalued to identify its definiteness. Results ：The monomer ginsenoside has definite antiarrhythimic action with sufficient evidence but insufficient evidences for the same action of total ginsenoside, stem and leaf ginsenoside, extracting solution of ginseng fruit, red ginseng decoction and ginseng preparation, which needs further large sample study. Conclusion ： Monomer ginsenoside has significant antiarrhythimic action.