超声心动图对不同分型二叶式主动脉瓣的临床特征探讨

Clinical and echocardiographical features of different types of bicuspid aortic valve

目的：探讨不同分型二叶式主动脉瓣（bicuspid aortic valve,BAV）患者的超声心动图及临床特征。方法：回顾性分析2010年1月—2015年12月在同济大学附属东方医院明确诊断为BAV患者的超声心动图及临床特点。结果：66例BAV患者年龄为8~91岁,其中男性（40例）平均年龄为（45.46±17.49）岁,女性（26例）平均年龄为（44.93±18.88）岁。男女患者之间年龄差异无统计学意义（P〉0.05）。42例并发主动脉瓣狭窄（aortic stenosis,AS）,平均年龄为（48.15±18.67）岁;12例并发主动脉瓣反流（aortic regurgitation,AR）,平均年龄为（44.33±19.03）岁。并发AR者比并发AS者更年轻（P〈0.05）。BAV患者不同分型中,R-L型46例（69.7%）、R-N型17例（25.8%）、L-N型3例（4.5%）。三型之间并发AS、AR及升主动脉增宽的差异无统计学意义（P〉0.05）。结论：BAV男女患者之间年龄差异无统计学意义;BAV并发AR者比并发AS者更年轻;不同分型BAV患者之间并发AS、AR及升主动脉增宽的差异均无统计学意义。

Objective：To explore the clinical and echocardiographical features of different types of bicuspid aortic valve （BAV）.Methods：Echocardiographic and clinical data of 66 BAV cases who admitted to East Hospital, Tongji University, from January 2010 to December 2015 were retrospectively analyzed.Results：The age of 66 cases of BAV ranged 8 to 91 years. The mean age of males （40 cases） was （45.46＆#177;17.49） years and of females （26 cases） was （44.93＆#177;18.88） years. There was no signiifcant difference in age between males and females （P〉0.05）. There were 42 cases complicated with aortic stenosis （AS） and 12 cases with aortic regurgitation （AR）. Statistical analysis showed that the cases complicated with AR were younger than those with AS （P〈0.05）. There were 46 cases with R-L type （69.7%）, 17 cases with R-N type （25.8%）, and 3 cases with L-N type （4.5%）. There was no signiifcant difference in the occurrence of AS, AR and enlarged ascending aorta among different types of BAV （P〉0.05）.Conclusion：There is no signiifcant difference in age between male and female BAV cases. The BAV cases complicated with AR are younger than those with AS. There is no signiifcant difference in the occurrence of AS, AR and enlarged ascending aorta among different types of BAV.