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自身免疫性胰腺炎一例及文献复习

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摘要 目的 通过比较总结自身免疫性胰腺炎(autoimmune pancreatitis,AIP)的临床表现及特征,提高AIP的诊断水平.方法 通过回顾性分析本院收治的1例AIP病人的临床资料,并通过检索2005~2015年近10年间国内发表的文献,总结归纳AIP的临床资料.结果 AIP的临床表现主要为间歇性或进行性黄疸、腹部不适或轻度腹痛、体重减轻等.实验室检查主要为血清学改变,主要是高丙种球蛋白血症,IgG升高,尤其是IgG4升高.影像学特点包括胰腺弥漫性或局灶性肿大,或伴有“鞘膜样”低密度/信号边缘.病理可见胰腺组织内淋巴细胞、浆细胞浸润和实质纤维化.经过糖皮质激素治疗后病人的临床症状明显缓解是其显著特点.结论 AIP临床特征缺乏特异性,加强对AIP发病机制及临床表现等方面的认识,提高影像学等相关检查的诊断水平,同时重视激素治疗后病情变化情况,是目前对AIP诊断较为实用的方法.
出处 《腹部外科》 2016年第3期236-238,共3页 Journal of Abdominal Surgery
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