三黄愈疡煎治疗消化性溃疡临床疗效及对胃泌素水平的影响

Clinical Effect of Sanhuang Yuyang Jian for Peptic Ulcer and Its Effect on Gastrin

目的:观察三黄愈疡煎治疗消化性溃疡疗效及其对胃泌素水平的影响。方法:60例消化性溃疡患者随机分为2组各30例。治疗组给予三黄愈疡煎治疗,对照组给予奥美拉唑胶囊治疗。疗程6周。结果:总有效率治疗组90.0%,对照组86.7%,2组比较,差异无统计学意义(P>0.05)。治疗组治疗后血清胃泌素水平与本组治疗前比较,差异有统计学意义(P<0.05),而对照组前后血清胃泌素水平比较,差异无统计学意义(P>0.05)。2组治疗后血清胃泌素水平比较,差异有统计学意义(P<0.05)。不良反应发生率观察组3.33%,对照组23.33%,2组比较,差异有统计学意义(P<0.05)。结论:三黄愈疡煎治疗消化性溃疡疗效好,且能降低患者胃泌素水平,不良反应发生率低。

Objective： To observe the clinical effect of Sanhuang Yuyang Jian for peptic ulcer and its effect on Gastrin.Methods： Sixty cases of patients with peptic ulcer were divided into two groups, 30 cases in each group. The treatment group was given Sanhuang Yuyang Jian,and the control group received omeprazole capsule for 6 weeks. Results：The total effective rate in the treatment group was 90.0%,and was 86.7% in the control group,the difference being significant（P〈0.05）. The difference of levels of serum Gastrin in the treatment group before and after treatment were significant（P 〈 0.05）,while those in the control group before and after treatment were not significant（P〉 0.05）. Comparing the levels of serum Gastrin in two groups after treatment, differences were significant（P 〈0.05）. The adverse reaction incidence rate in the observation group was 3.33%,and was 23.33% in the control group,the difference being significant（P 〈 0.05）. Conclusions：The clinical effect of Sanhuang Yuyang Jian on curing peptic ulcer is effective. This treatment can reduce Gastrin and adverse reaction incidence rate.