血清降钙素原在肺结核疾病诊断与治疗中的意义

The procalcitonin in significance in diagnosis and treatment of tuberculosis disease

目的研究血清降钙素原（PCT）在肺结核病中的诊断以及治疗效果评估的价值。方法相应的选择293例初发性肺结核及107例经过治疗后的肺结核患者，分别测量其血清中PCT含量，除此之外还需检测肺部空洞性病变和胸膜积液状况，抽取293名无病症者血清实施参照，从而评定PCT的实际作用。结果不论是初发患者还是经过治疗患者，其PCT含量较健康人均明显升高（P〈0．05），而后者较前者明显有所降低（P〈0．01），同时影像学检查证实此过程肺部病变的情况也得到了有效的遏制。结论PCT对于肺结核病患在早期的诊断过程之中具有良好的指导作用，同时对于判断经过治疗患者的预后具有一定价值。

Objective To value the method of serum procalcitonin （PCT） in the TB diagnostic and treatment. Methods 293 newly diagnosed pulmonary tuberculosis and 107 patients after treatment of the disease were selected appropriately. We measured their serum PCT content. Meanwhile, we detected the pulmonary cavity and pleural effusion situation. We took 293 serum free conditions as enforce referential, which assessed the practical utility of PCT. Results Whether the patient was newly diagnosed or after treatment the content of the PCT patients compared to healthy group showed significantly difference （ P〈 0.05）, while the latter was significantly improved compared to the former （ P 〈0.01）, while the process of pulmonary disease has been effectively curbed. Conclusions The treatment of tuberculosis patients takes a good role in guiding the process of early diagnosis, which has good value for the patient after treatment prognosis.