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调神通络针刺法对缺血再灌注大鼠海马区Cx43 mGluR5 P38MAPK蛋白表达的影响及意义 被引量:3

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摘要 目的:探讨调神通络针刺法对缺血再灌注大鼠海马区Cx43、m GluR5、P38MAPK蛋白表达的影响及意义。方法:以调神通络针刺法为干预手段,以大鼠急性局灶性脑缺血再灌注模型作为研究对象,运用Western blot方法检测大鼠海马区Cx43、m GluR5、P38MAPK蛋白的表达情况,进而推断调神通络针刺法对半通道的调控作用。结果:Western blot检测各组间Cx43、m GluR5、P38MAPK蛋白表达灰度值比较,差异均有统计学意义(P<0.05)。结论:调神通络针刺法对缺血再灌注大鼠海马区Cx43、m GluR5、P38MAPK蛋白有一定的调控作用,进而影响缺血性脑损伤时半通道的开放,产生脑保护作用。
出处 《四川中医》 2016年第7期62-63,共2页 Journal of Sichuan of Traditional Chinese Medicine
基金 天津市科委基金(编号:14JCZDJC36800)
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