摘要
目的:观察不同治疗预防阿司匹林致老年上消化道出血的疗效,探讨其理想预防方案。方法:选择老年人预防性服用阿司匹林患者60例,随机分成治疗1组(雷贝拉唑+阿司匹林)、治疗2组(乌芍散+阿司匹林)和对照组(阿司匹林)各20例。观察2组上消化道症状及胃肠黏膜损伤发生率。结果:对照组的上消化道症状发生率明显高于治疗1组和治疗2组,差异有统计学意义(P<0.01),对照组的胃肠黏膜损伤发生率也明显高于治疗1组和治疗2组,差异有统计学意义(P<0.05)。但两个治疗组的上消化道症状和胃肠黏膜损伤发生率相比较,无统计学差异(P>0.05)。结论:雷贝拉唑、乌芍散均能有效地降低阿司匹林致老年人上消化道出血的发生率。
Objective: To analyze and compare the effectiveness of different protocols on prevention upper gastrointestinal bleeding in elderly with taking aspirin. Methods: 60 cases in elderly taking aspirin on prevention were randomly divided into treatment group 1,treatment group 2and controlled group. The treatment group 1was treated with rabeprazole and aspirin,the treatment group 2was treated with Wushao Powder and aspirin,the controlled group was treated with aspirin. The gastrointestinal adverse reactions and mucosal injury scores was analyzed. Results: The gastrointestinal adverse reactions of the controlled group was significantly higher than the treatment group 1and the treatment group 2( P〈0. 01),the mucosal injury scores of the controlled group was significantly higher than the treatment group 1and the treatment group 2( P0. 05),but the gastrointestinal adverse reactions and mucosal injury scores in the treatment group 1was not statistically significant than the treatment group 2( P〈0. 05).Conclusion: Rabeprazole and Wushao Powder can effectively decrease the upper gastrointestinal bleeding rate in elderly with taking aspirin.
出处
《四川中医》
2016年第7期150-152,共3页
Journal of Sichuan of Traditional Chinese Medicine
关键词
雷贝拉
乌芍散
阿司匹林
上消化道出血
Rabeprazole
Wushao Powder
Aspirin
Upper gastrointestinal bleeding