食管黏膜病变术前胃镜活检病理的价值分析

Value Analysis of Pathological Biopsy Before Surgery of Patients With Esophageal Mucosal Lesions

目的探讨食管黏膜病变术前胃镜活检病理的应用价值。方法选取我院胃镜活检诊断为食管黏膜病变,行内镜黏膜下剥离术治疗的400例患者,比较术前胃镜活检病理与术后病理的差异。结果术前胃镜活检病理与术后病理完全一致率为62.3%(249/400)。上皮内瘤变组术前胃镜活检与术后病理诊断符合率低于早期食管癌组(P<0.01)。结论食管黏膜病变术前胃镜活检病理对于诊断有较好的提示价值,但并不能据此完全正确判断病变的性质,需对疾病进行积极的治疗并通过术后病理获得更加准确的诊断。

Objective To discuss the application value of pathological biopsy before surgery of patients with esophageal mucosal lesions.Methods 400 patients with esophageal mucosal lesions diagnosed by pathological biopsy and treated with endoscopic submucosal dissection were chosen and the results of pathological before and after surgery were compared.Results The concordance rate of pathological biopsy before surgery and after surgery was 62.3%（249/400）.The concordance rate of pathological before and after surgery in intraepithelial neoplasia group was lower than early esophageal cancer group（P〈0.01）.Conclusion Pathological biopsy before surgery of patients with esophageal mucosal lesions has better prompt value for diagnosis,but it should not determine the nature of the lesion exact correct,it need aggressive treatment and pathological diagnosis after surgery to get more accurate diagnosis.