克拉霉素治疗慢性鼻-鼻窦炎的临床疗效分析

Analysis of Clinical Efficacy of Clarithromycin in the Treatment of Chronic Rhinosinusitis

目的分析探讨克拉霉素治疗慢性鼻-鼻窦炎的临床疗效。方法选取我院2013年4月~2015年5月收治的86例慢性鼻-鼻窦炎患者,随机分为观察组和对照组,观察组患者接受克拉霉素的治疗,对照组患者接受阿莫西林克拉维酸钾的治疗,对比临床疗效。结果观察组患者不良反应发生率为9.30%,治疗有效率为90.70%,均优于对照组患者（分别为25.58%、72.09%）,组间比较差异具有统计学意义（P〈0.05）。结论克拉霉素治疗慢性鼻-鼻窦炎临床效果较好。

Objective To investigate the chronic nasal clarithromycin treatment-sinusitis clinical efficacy. Methods 86 cases of chronic rhinosinusitis patients were chose in our hospital from April 2013 to May 2015, were randomly divided into observation group and control group, the observation group patients receiving clarithromycin therapy, the control group of patients receiving amoxicillin amoxicillin clavulanate potassium treatment, comparison of clinical efficacy after treatment. Results The incidence of patients with bad hair should be 9.30%, the effective rate was 90.70%, significantly better than the control group（respectively 25.58%, 72.09%）, a statistically significant difference between groups（P〈0.05）.Conclusion Exploration clarithromycin treatment of chronic rhinitissinusitis clinically significant.