奥美拉唑联合硫糖铝治疗急性出血性胃炎临床疗效观察

The Clinical Efficacy of Omeprazole and Sucralfate in Acute Hemorrhagic Gastritis

目的探讨奥美拉唑联合硫糖铝治疗急性出血性胃炎的临床效果。方法选取我院收治的102例急性出血性胃炎患者,并随机分为两组,对照组给予常规治疗,观察组接受常规治疗以及奥美拉唑和硫糖铝联合治疗。观察并比较两组患者治疗后的出血量、住院时间、止血时间以及药物不良反应发生情况。结果观察组平均出血量、平均止血时间和平均住院时间低于对照组(P<0.05);观察组药物不良反应发生率为3.9%,低于对照组的15.7%(χ2=3.99,P=0.04)。结论硫糖铝与奥美拉唑联合治疗急性出血性胃炎能够快速止血,有效缩短住院时间与出血时间,且不良反应发生率较低。

Objective In order to investigate the clinical efficacy of omeprazole and sucralfate in acute hemorrhagic gastritis. Methods 102 cases of acute hemorrhagic gastritis patients were selected, and randomly divided into two groups, control group received conventional treatment, study group received conventional treatment, as well as omeprazole and sucralfate. The blood loss, hospital stay, bleeding time, and the incidence of adverse drug reactions in two groups were compared. Results The average blood loss, average bleeding time and hospital stay in the study group were significantly lower than the control group（P〈0.05）, adverse drug reactions was 3.9% in the study group, significantly lower than the 15.7% in the control group（χ2=3.99, P=0.04）. Conclusion Sucralfate and omeprazole in acute hemorrhagic gastritis can quickly stop the bleeding, shorter hospital stays and effective bleeding time, with low incidence of adverse reactions.