正念训练干预对乳腺癌患者化疗后癌因性疲乏的研究

Effect of mindfulness training intervention on cancer related fatigue after chemotherapy in patients with breast cancer

目的探讨正念训练对乳腺癌患者癌因性疲乏（CRF）的影响。方法将2015年1-6月该院收治的200例中青年乳腺癌化疗患者分为观察组和对照组（各100例）,对照组给予常规护理,观察组在对照组的基础上给予正念训练,并参照癌症疲乏量表（CFS）评价患者的疲乏状况,并比较干预前后两组CRF各维度及总疲乏评分。结果乳腺癌术后化疗患者绝大多数存在疲乏症状,CRF发生率为97.0%,以中度疲乏为主,其次为轻度疲乏,重度疲乏最少。在第2次化疗时,两组患者躯体疲乏、认知疲乏、情感疲乏及总疲乏评分比较,差异均无统计学意义（P〉0.05）;第4、6次化疗时,观察组躯体疲乏、认知疲乏、情感疲乏及总疲乏评分均低于对照组,差异均有统计学意义（P〈0.05）。结论正念训练干预可以明显缓解患者的疲乏状态,提高患者的生活质量。

Objective To investigate the effects of mindfulness training on cancer related fatigue（CRF）in patients with breast cancer.Methods Two hundreds young and middle-aged patients with breast cancer receiving chemotherapy in our hospital from January to June 2015 were divided into the observation group and control group,100 cases in each group.The control group was given the routine nursing,while on this basis the observation group was given the mindfulness training.The cancer related fatigue status was evaluated according to the CFS scale.The CFS various dimensions and total fatigue scores before and after intervention were compared between the two groups.Results The fatigue status existed in most of patients with breast cancer after chemotherapy,the occurrence rate of CRF was 97.0%,which was dominated by moderate fatigue,followed by mild fatigue,severe fatigue was minimal;the body fatigue,cognitive fatigue,emotional fatigue and total fatigue scores in the second time of chemotherapy had no statistically significant differences between the two groups（P〈0.05）;in the fourth and sixth time of chemotherapy,the body fatigue,cognitive fatigue,emotional fatigue and total fatigue scores in the observation group were significantly lower than those in the control group,the differences were statistically significant（P〈0.05）.Conclusion The mindfulness training intervention can relieve the fatigue status and improve the living quality of the patient.